First in Human

How Two Founders Turned an Unsolvable ICU Problem into a Medtech Breakthrough


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Some problems in medicine see so many failed attempts that they start to feel untouchable. Teams learn to move on, investors grow wary, and the problem becomes its own warning label. Kate Garrett and Dr. Dan Azagury chose a different path. 

Kate and Dan, cofounders of Ciel (later acquired by Vyaire Medical), found themelves confronted with one of those notoriously unsolved, high-stakes problems - the kind that had stopped other companies cold. What happened next changed everything for them, their patients, and for medtech. 

In this episode, Kate and Dan share how confronting that kind of problem shaped their partnership, what the journey taught them about trust and perseverance, and why some of the most meaningful breakthroughs begin with the problems everyone else have learned to avoid. 


Subscribe to First in Human: 
- Apple Podcasts: https://podcasts.apple.com/us/podcast/first-in-human/id1842644737 
- Spotify: https://open.spotify.com/show/3C1xG5SxPei8m2lI63WSkd 


Connect with Kate and Dr. Azagury: 
Kate Garrett's LinkedIn: https://www.linkedin.com/in/kate-garrett-464920/ 
Dr. Dan Azagury's LinkedIn: https://www.linkedin.com/in/dan-azagury-ba70733a/ 


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First in HumanBy David Hindin

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