Klaatu reviews the card game series, Fluxx.

http://boardgamegeek.com/geeksearch.php?action=search&objecttype=boardgame&q=fluxx&B1=Go

https://en.wikipedia.org/wiki/Fluxx

Fluxx is a card game, played with a specially designed deck published by Looney Labs. It is different from most other card games, in that the rules and the conditions for winning are altered throughout the game, via cards played by the players.