This week, a black market and community network of cat lovers sprang into existence to help pet parents get access to an illegal lifesaving drug for a cat disease called FIP. But a massive revelation threatens to tear this community apart. 

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LINKS

Nicole Randall Sentencing Release

FIP Vet Guide

FIP Warriors

When Marlena's cat was diagnosed with a terminal disease, she found herself seeking help not from a vet, but a series of websites and Facebook groups. The first in a three-part series.

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LINKS:

GS treatment available in pharmacies: https://bestfriends.org/sites/default/files/2024-11/Network_09%20Webinar_FIP%20Treatment_US-Pharmacy-FIP-Treatment-Options.pdf

Dr. Pedersen's 2019 paper

FIP Warriors Facebook Group

Gilead's statement: 

Since Gilead identified GS-441524 as a potential treatment for cats with feline infectious peritonitis (FIP), we made it available to institutions with the expertise to advance medicines for veterinary use. This is why we shared GS-441524 with UC Davis to research its impact on FIP.

GS-441524 is an intermediate in the synthesis of remdesivir, an approved treatment for COVID-19. Gilead’s supply of GS-441524 was and continues to be used to manufacture remdesivir to meet the demands of COVID-19.

Today, remdesivir has been made available to more than 14.5 million patients around the world, including more than 8.1 million in low- and lower-middle income countries.

In parallel, Gilead has made progress in studies identifying prodrugs of GS-441524 with improved oral bioavailability that could be further investigated as a therapeutic for FIP in cats. Discussions with suitable veterinary specialty companies are ongoing, but to-date we have not identified an appropriate partner. Gilead supports finding a solution for FIP at the earliest opportunity.

This week, we're running an episode of one of our favorite shows, The Dream, hosted by Jane Marie. At the top of this episode I talk to Jane Marie about her show, and the fact that we went to the same high school and didn't know each other (true story!) 

THIS EPISODE:

This past year Charlotte Isenberg, a once-popular teen anti-abortion activist, found herself switching sides in this national debate. What happened to her next is unprecedented and a warning for parents and kids alike.

Find Charlotte on Tik Tok here:

LINKS:

Follow Charlotte on TikTok Here

Listen to The Dream

iTunes
Spotify
PocketCasts

Follow Jane Marie on:

Instagram
BlueSky
TikTok

Special unlocked bonus ep! And a note at the top from Alex!

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Astrid, the star of the episode Little by Little, talks about recreating an impossible instrument from an iconic episode of Star Trek in real life.

LINKS:

The Aldean Instrument

Astrid's Keynote at the Audio Developer Conference

Commander Riker Sits Down

Ali's house burnt down in this year's Los Angeles fires and took her entire life with it. Well almost her entire life. And she wants our help to make sure she doesn't lose one of the few precious things that survived the fire.

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Astrid designs music hardware, and specifically circuitboards. And over the past few years, she's fallen in love with a specific font. But the software the font is in is being discontinued, and there's no way to export it. Where did it come from? Can she rescue it from the program it’s trapped in?

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LINKS:

The Little Character Font Set

Bela

The Albert Einstein Institute

This week: Kyle has a medal that was awarded to his great great great Grandfather over a century ago. Was it awarded by a shadowy secret society? We investigate.

THE FRONT OF THE MEDAL

THE BACK OF THE MEDAL

Link to Andrew J. Seymour's book "The World's Greatest"

For Premium Hyperfixed listeners, we included some supplementary research material, photos and news clippings. If you'd like to see them, or if you'd simply like to support independent journalists, you can beome a premium subscriber below!

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This week: Somehow, a movie release in 2014 has disappeared off the internet. It can't be streamed, it can't be torrented, you can't even buy a physical copy. Parker needs to see it.

LINKS: 

Missing Movies

The Day the Clown Cried

The Missing Dr. Who Episodes

I Am Obsessed With You But You've Got to Leave Me Alone

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Intrigue on the high seas. I mean on land. 

LINKS: 

Jenny Phenix's legal complaint against Villa Vie

This week - Scammers have managed to copy Jordan's entire website and steal her business -- more than once. But how are they doing it? And why is it so hard to fight now? 

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LINKS:

StoreLock

ICANN

What is the GDPR