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This week on Bench Boost our team reviews special considerations for measuring lithium by ICP-OES and ICP-MS. They discuss common lithium sample types and preparation guidance. Autumn emphasizes the impact of high total dissolved solids (TDS) and easily ionizable elements (EIEs) causing plasma ionization-balance shifts and signal suppression for some sample types. Additional tips include selecting appropriate internal standards, choosing suitable emission lines, and avoiding error propagation during large dilutions.