In this episode of SciBud, join your host Maple as we explore groundbreaking research from the CUPAL study, which investigates risk factors for visual field progression in primary angle-closure disease (PACD) over a decade. Discover how nearly a third of patients showed signs of worsening vision, especially among those with primary angle-closure glaucoma (PACG), where the rate was alarmingly high at 44%. Delve into the key findings that identified higher fluctuations in intraocular pressure and steeper initial visual field index slopes as significant indicators of deterioration. We’ll also unpack the study’s merits—including its extensive follow-up strategy—while critiquing aspects like data reproducibility. As we learn about the links between eye shape and glaucoma risk, you'll understand how this research can drive tailored management strategies for patients, helping to mitigate vision loss. Join us for an enlightening conversation that highlights the evolving landscape of bioimaging and ocular health! Link to episode page with article citation: www.scibud.media/podcast/season/2025/episode/101