PaperPlayer biorxiv microbiology

Immunoreactive peptide maps of SARS-CoV-2 and other human coronaviruses


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Link to bioRxiv paper:
http://biorxiv.org/cgi/content/short/2020.08.13.249953v1?rss=1
Authors: Mishra, N., Huang, X., Joshi, S., Guo, C., Ng, J., Thakkar, R., Wu, Y., Dong, X., Li, Q., Pinapati, R., Sullivan, E., Caciula, A., Tokarz, R., Briese, T., Lu, J., Lipkin, W. I.
Abstract:
Serodiagnosis of SARS-CoV-2 infection is impeded by immunological cross-reactivity to the human coronaviruses (HCoV) SARS-CoV-2, SARS-CoV-1, MERS-CoV, OC43, 229E, HKU1, and NL63. Here we report the identification of humoral immune responses to SARS-CoV-2 and other HCoV peptides that can be used to detect asymptomatic, mild and, severe SARS-CoV-2 infections, and may enable the discovery of biomarkers for immunity following infection or vaccination.
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