"Poison" delves into the complexities of life in Bulawayo, exploring themes of ambition, community, and the contrasting realities that exist within society. The lyrics paint a vivid picture of everyday life, referencing local slang ("boyzen," "Hao le monate lempitse") and cultural touchstones, while also touching on universal themes of success and perseverance. Lines like "Another man's gango’s another man's poison / Another man's op is another man's boyzen" highlight the subjective nature of perception.