This podcast utline Patient Group Directions (PGDs) for pharmacists in England to supply antibiotics for infected insect bites and stings as part of the Pharmacy First service. Each PGD focuses on a specific antibiotic: flucloxacillin as the primary treatment, clarithromycin as an alternative for those with penicillin allergies, and erythromycin specifically for pregnant individuals with penicillin allergies. They detail the criteria for identifying eligible patients, conditions that exclude individuals from receiving treatment under the PGD, necessary training and competency requirements for pharmacists, and the dosage and administration of each antibiotic. The documents also provide information on potential drug interactions, management of adverse reactions, and the required record-keeping procedures.