What are the challenges, and potential missteps, when it comes to reprocessing bronchoscopes, GI endoscopes and ureteroscopes? How have guidelines and standards evolved? And how has COVID-19 flipped the script when it comes to pursuing evidence-based strategies to eliminate infections related to endoscopes? We explore these questions and more with Dr. Hudson Garrett, CEO of Community Health Associates LLC in Atlanta and co-founder of the nonprofit Infection Prevention Institute.