This epic storyline features the ultimate battle for the universe as Thanos, one of the most powerful villains in the Marvel Universe, seeks to obtain the power of the Infinity Stones.

To stop Thanos and his quest for ultimate power, Earth's Mightiest Heroes team up with cosmic beings such as the Guardians of the Galaxy, the Nova Corps, and the Silver Surfer. Together, they must protect the universe from Thanos and his army of minions.