A multicenter randomized clinical trial in Finland has found that, among patients initially treated with antibiotics for uncomplicated acute appendicitis, the rate of recurrence and appendectomy at 10-year follow-up supports the use of antibiotics. In this episode, host Rick Greene, MD, FACS, talks with Paulina Salminen, MD, PhD, FACS(Hon), from the University of Turku in Finland, who is lead author of the study, Antibiotic Therapy for Uncomplicated Acute Appendicitis Ten-Year Follow-Up of the APPAC Randomized Clinical Trial, in The Journal of the American Medical Association.

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