The importance of preventing injury and increasing performance specific to sport among athletes is a top priority for coaches and players. This is especially true for female collegiate athletes who have a high rate of ACL injuries, especially non-contact ACL ruptures. Females have multiple risk factors associated with the type of injury, which includes both internal and external factors. Various ACL prevention methods have been promoted that help reduce the risk as well as increase performance specific to different sports. Two specific ACL prevention programs discussed in this review paper are Sportsmetric and the PEP program. These programs specialize in ACL injuries and use multiple exercises and drills including; plyometrics, muscle strengthening, stretching, proprioception, and landing techniques. Studies have shown these programs are effective and help reduce ACL injuries, which is most needed amongst the female collegiate athlete population.