In this episode, Tadd Lane discusses recent advancements in weight loss medications, particularly focusing on a new pill called Orforglyprone, which shows promise in clinical trials for aiding weight loss in individuals with type 2 diabetes. The conversation then shifts to the discovery of potential signs of life on the exoplanet K2-18b, as observed by the James Webb telescope. Finally, Tadd delves into the psychology of memory, particularly why we remember embarrassing moments and how our brains process emotions, emphasizing the importance of emotional intelligence.