One year ago, President Biden reignited the Cancer Moonshot initiative and set bold new goals to reduce the cancer death rate by at least 50% over the next 25 years and to improve the lives of cancer patients and survivors, their caregivers and families. In an interagency effort, the White House Cancer Cabinet has brought together leaders from across government to progress priority actions on ending cancer as we know it. Dr. Danielle Carnival, White House Cancer Moonshot Coordinator, lays out those actions and the initial progress being made toward these goals.