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Generic Name

Insulin detemir, Insulin glargine

Trade Name

Levemir, Lantus

Indication

hyperglycemia with diabetes type 1 and 2, diabetic ketoacidosis

Action

stimulates uptake of glucose into muscle and fat cells, inhibits production of glucose in the liver, prevents breakdown of fat and protein

Route Onset Peak Duration Detemir 3-4 hr 3-14 hr 24 hr Glargine 3-4 hr none 24 hr

Therapeutic Class

antidiabetics, hormones

Pharmacologic Class

pancreatics

Nursing Considerations

• assess for symptoms of hypoglycemia or hyperglycemia • monitor body weight over time • may cause decreased inorganic phosphates, potassium, and magnesium • monitor blood sugars every 6 hours, monitor A1C every 3-6 months