This systematic review evaluates the efficacy of specialized nursing care in mitigating the adverse physical and psychological effects associated with breast cancer treatment. By analyzing decades of clinical trials, the study demonstrates that structured interventions—ranging from emotional support to care coordination—significantly reduce common burdens such as chronic fatigue, pain, and mental distress. The text highlights that nurse-led strategies are not merely supplementary but are essential for enhancing the quality of life and overall well-being of patients. Ultimately, the source serves as a call for integrating comprehensive, patient-centered care into standard oncological practice to optimize recovery outcomes.