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Interneuron diversity is required for compartment-specific feedback inhibition
Link to bioRxiv paper:
http://biorxiv.org/cgi/content/short/2020.11.17.386920v1?rss=1
Authors: Keijser, J., Sprekeler, H.
Abstract:
Cortical inhibitory interneurons consist of many subtypes that have been associated with different functions. Here we use an optimization approach to show that two classes of interneurons are necessary to implement compartment-specific feedback inhibition to pyramidal cells. The two classes resemble PV-expressing and SST-expressing interneurons in their connectivity and short-term plasticity, suggesting a functional role for their diverse characteristics.
Copy rights belong to original authors. Visit the link for more info
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Link to bioRxiv paper:
http://biorxiv.org/cgi/content/short/2020.11.17.386920v1?rss=1
Authors: Keijser, J., Sprekeler, H.
Abstract:
Cortical inhibitory interneurons consist of many subtypes that have been associated with different functions. Here we use an optimization approach to show that two classes of interneurons are necessary to implement compartment-specific feedback inhibition to pyramidal cells. The two classes resemble PV-expressing and SST-expressing interneurons in their connectivity and short-term plasticity, suggesting a functional role for their diverse characteristics.
Copy rights belong to original authors. Visit the link for more info