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Ovarian reserve testing is widely used — but interpretation requires nuance.

In this episode, Dr. Erica Bove reviews a practical framework for interpreting AMH, antral follicle count (AFC), FSH, and estradiol in clinical practice, with emphasis on how those values influence treatment strategy.

Discussion includes:

• AMH as a surrogate for cohort size and medication responsiveness

• AFC correlation and discordance with AMH

• Elevated FSH as a compensated ovarian state

• Brain–ovary feedback physiology

• FSH resistance and stimulation response

• IVF medication dosing considerations

• Predicting ovarian response and hyperstimulation risk

• Why ovarian reserve is not synonymous with fertility

Rather than weighting one marker over another, Dr. Bove outlines a physiology-based framework that integrates laboratory values, age, genetics, and reproductive goals into individualized treatment planning.

This discussion is part of Season 1 of the Love & Science Fertility Framework: The Biology Beneath the Surface — a series examining the physiology that drives reproductive outcomes.

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As always, please keep in mind that this is my perspective and nothing in this podcast is medical advice.

If you found this conversation valuable, book a consult call with me using this link:

https://www.loveandsciencefertility.com/private-fertility-consult

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Please don’t let infertility have the final word. We are here to take the burden from you so that you can achieve your goal of building your family with confidence and compassion. I’m rooting for you always.

In Gratitude,

Dr. Erica Bove