Tukua

Intervenciones alimentarias en la Gota


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¡Gracias por escuchar! Una pregunta importante para los pacientes y médicos es si, y en qué medida, las intervenciones dietéticas, los suplementos dietéticos o la pérdida de peso pueden ayudar a prevenir la gota incidente o controlar la gota existente. En este episodio se revisará evidencia evidencia reciente en este sentido, derivada de uno de los pocos ensayos clínicos relacionados a este tema.
Algunas referencia útiles:
Singh, J. A., Shah, N. & Edwards, N. L. A cross-sectional internet-based patient survey of the management strategies for gout. BMC Complement. Altern. Med. 16, 90 (2016).
Juraschek, S. P. et al. Effects of dietary patterns on serum urate: results from the DASH randomized trial. Arthritis Rheumatol. https://doi.org/10.1002/art.41614 (2020).
Appel, L. J. et al. A clinical trial of the effects of dietary patterns on blood pressure. DASH Collaborative Research Group. N. Engl. J. Med. 336, 1117–1124 (1997).
Jacobs, D. R. Jr. & Steffen, L. M. Nutrients, foods, and dietary patterns as exposures in research: a framework for food synergy. Am. J. Clin. Nutr. 78, 508s–513s (2003).
Juraschek, S. P. et al. Effects of the Dietary Approaches to Stop Hypertension (DASH) diet and sodium intake on serum uric acid. Arthritis Rheumatol. 68, 3002–3009 (2016).
Li, C., Hsieh, M. C. & Chang, S. J. Metabolic syndrome, diabetes, and hyperuricemia. Curr. Opin. Rheumatol. 25, 210–216 (2013).
Stamp, L. K. et al. Clinically insignificant effect of supplemental vitamin C on serum urate in patients with gout: a pilot randomized controlled trial. Arthritis Rheum. 65, 1636–1642 (2013).
Stamp, L. K. et al. Lack of effect of tart cherry concentrate dose on serum urate in people with gout. Rheumatology 59, 2374–2380 (2020).
Singh, J. A. et al. A randomized internet-based pilot feasibility and planning study of cherry extract and diet modification in gout. J. Clin. Rheumatol. 26, 147–156 (2019).
Rai, S. K. et al. The Dietary Approaches to Stop Hypertension (DASH) diet, Western diet, and risk of gout in men: prospective cohort study. BMJ 357, j1794 (2017).
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TukuaBy Daniel Xibille Friedmann