Intellectually Curious

Ion Channels: The Tiny Gates Powering Life


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A clear, fast-paced tour of ion channels—the membrane gates that make nerves fire, hearts beat, and hormones release. We’ll unpack the electrochemical gradient, the selectivity filter that distinguishes potassium from sodium, and how voltage- and ligand-gated signals open or close these channels. Explore pharmacology and diseases like cystic fibrosis, the landmark structural work solved by MacKinnon, and how Markov models help predict their behavior—bridging biology, physics, and medicine.


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Intellectually CuriousBy Mike Breault