One of the most common question men with prostate cancer ask us at Cancer ABCs is if they can stop their hormone therapy (ADT) when they go on a second generation hormone treatment like abiraterone (Zytiga).

A recent analysis of the SPARE Trial points us in the direction that it might be possible to halt ADT when you are taking Zytiga.  SPARE was a small trial which needs to be replicated by a larger trial before we can gain confidence in this conclusion. 

SPARE did not evaluate what, if any change. stopping ADT  when you are on Zytiga might have on survival, economic costs and the quality of life.  

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