Aging has long been treated as inevitable. But what if it’s not? What if aging is, at its core, a problem to be solved? In this episode, I speak with biomedical gerontologist Aubrey de Grey about the most ambitious anti-aging experiment ever conducted on mice. The Robust Mouse Rejuvenation (RMR) study, spearheaded by Aubrey and the Longevity Escape Velocity Foundation, aims to extend both the average and maximum lifespan of mice by at least 12 months—a staggering leap in a species that typically lives around 30 months. We unpack the science behind this bold endeavor: What is aging? Why aim for rejuvenation and damage repair as opposed to slowing down aging? What interventions are being trialed in mice? What are the best achievable results? What does the blueprint for longevity escape velocity look like?