Accurate clinical interpretation of somatic cancer variants is critical for diagnosis and guidance of precision oncology treatment. Without shared standards, laboratories and clinical decision-support (CDS) systems have implemented independent approaches, leading to significant variability and highlighting a need for standardization. 

Through a collaborative effort, ClinGen, the Cancer Genomics Consortium (CGC) and the Variant Interpretation for Cancer Consortium (VICC) have developed a framework for standardized classification. In this webinar, we will evaluate these standards and compare their classifications with results from the QIAGEN Clinical Insight (QCI) Interpret CDS system.

You will learn: 

• Understand ClinGen/CGC/VICC standards for variant classification
  Learn how these expert-developed guidelines define and standardize somatic cancer variant classification.

• Compare software classifications with guideline-based human assessments
  See how classifications from the ClinGen/CGC/VICC standards compare with those generated by QCI Interpret.

• Best practices to use guidelines and tools together
  Discover how to combine expert guidelines with clinical decision support tools for more reliable variant interpretation.