The Real GI Doc Show

Is Marijuana Use Making You Sick? Understanding Cannabinoid Hyperemesis Syndrome.

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In this episode, Dr. Gandolfo explores a lesser-known side effect of heavy marijuana use: Cannabinoid Hyperemesis Syndrome (CHS). Although marijuana use is becoming even more prevalent, awareness of this severe vomiting illness still remains low.

Dr. Gandolfo shares a compelling case study of a young patient suffering from CHS, detailing the symptoms, diagnosis, and treatment options available for this condition.

Topics covered in this episode:

  • Understanding Cannabinoid Hyperemesis Syndrome and its link to cyclic vomiting syndrome.
  • The phases of cyclic vomiting and how they relate to CHS.
  • The physiological mechanisms behind CHS, including the role of CB receptors and THC.
  • The impact of high THC concentrations in modern marijuana products.
  • Complications associated with CHS, from dehydration to more serious issues.
  • Strategies for managing CHS, including the importance of long-term cessation of marijuana use.
  • The role of therapy and medication in treating underlying anxiety and depression linked to heavy cannabis use.

    • Referenced in today's episode:

    AGA Clinical Practice Update on CHS (2024)

    Be sure to subscribe to The Real GI Doc Show for more insights, and reach out with your questions on social media @realgidoc or leave an audio question for Dr. Gandolfo here.

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    The Real GI Doc ShowBy Fred Gandolfo, MD
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