Welcome all to IS PHARMACOLOGY DIFFICULT Podcast ! I am Dr Radhika Vijay and in today's episode I will communicate about especially Phase 1 reactions , also known as Nonsynthetic or Functionalisation reactions. The most important of the different phase 1 reactions amongst oxidation, reduction and hydrolysis reactions are oxidation reactions, they are carried out by Mixed functional oxidases enzyme group, abbreviated as MFO Enzymes. The most important of these is large superfamily of heamproteins , i.e. cytochrome P450 enzymes, which metabolise many chemical from environment, diet and drug.Oxidation reaction means addition of oxygen , or removal of hydrogen. There may be different types of oxidation namely hydroxylation, N/O- dealkylation, oxidative deamination, etc.Firstly a short lived intermediate of the type quinone, epoxide or superoxide which converts to stable form. Further comes a new chapter branching out today i.e. different microsomal enzymes and their action and so much more to account for, so come on, its a weekend!! And new leaflet should turn over on a new day, which will be Monday for us, till then, please rate and review on apple podcasts, itines store, stay tuned, HAPPY LEARNING ON A HAPPY SUNDAY!Thank you!!