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Is Pharmacology Difficult Podcast PLASMA PROTEIN BINDING INTRODUCTION
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! As I promised yesterday, I am here with a brand new type of barrier and the topic goes as Plasma Protein Binding. Today is simply the Introduction to this important, extensive and must to be understood topic. Firstly comes the background description which explains that drug partly exists in free form and partly in bound form! But these two forms always exist in dynamic equilibrium and in a sort of reversible equation given as:
FREE DRUG+PROTEIN -- DRUG PROTEIN COMPLEX
Free fraction is active, undergoes metabolism, excretion while bound form is inert , inaccessible or inactive! It serves as reservoir and prolongs duration of action. But these are two forms always in equilibrium, that's the background image of tomorrow's real story of plasma protein binding, hope you all like it! Till next episode, do follow me here, stay tuned, thank you!
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By Dr Radhika VijayWelcome all to IS PHARMACOLOGY DIFFICULT Podcast! As I promised yesterday, I am here with a brand new type of barrier and the topic goes as Plasma Protein Binding. Today is simply the Introduction to this important, extensive and must to be understood topic. Firstly comes the background description which explains that drug partly exists in free form and partly in bound form! But these two forms always exist in dynamic equilibrium and in a sort of reversible equation given as:
FREE DRUG+PROTEIN -- DRUG PROTEIN COMPLEX
Free fraction is active, undergoes metabolism, excretion while bound form is inert , inaccessible or inactive! It serves as reservoir and prolongs duration of action. But these are two forms always in equilibrium, that's the background image of tomorrow's real story of plasma protein binding, hope you all like it! Till next episode, do follow me here, stay tuned, thank you!