Is psoriasis genetic, and how much of the risk is inherited in Europe?

Psoriasis genetics explained: autoimmune skin disease, polygenic risk, family history, immune dysregulation, and environmental triggers.

In this episode, we examine whether psoriasis runs in families and how doctors assess inherited risk under EU medical guidance.

You’ll learn:

• What psoriasis is (a chronic immune-mediated inflammatory condition)

• How multiple genes contribute to susceptibility (polygenic inheritance)

• The role of HLA-related genetic factors

• Why family history increases risk but does not guarantee disease

• Environmental triggers: infection, stress, skin injury, certain medications

• The difference between plaque psoriasis and psoriatic arthritis

• When joint pain or nail changes require further assessment

• Situations where systemic treatment requests may require specialist review

We explain how doctors assess symptom pattern, plaque distribution, joint symptoms, family history, cardiovascular risk factors, and previous treatments during an online consultation in the EU. Genetics increase susceptibility, but disease expression depends on immune and environmental factors.

This episode reflects the clinical standards used by Mobi Doctor, where dermatology consultations are reviewed by a registered physician in line with EU medical guidance.

Read the full guide and transcript here:

https://www.mobidoctor.eu/blog/is-psoriasis-genetic