In this episode you’ll get to hear two extended excerpts from a long conversation that myself and several of my Cannabis science colleagues had about Cannabis quality, chemistry, and beyond at the end of the American Chemical Society Spring Conference on March 27th, 2025.

The conversation was recorded at Abstrax Headquarters in Irvine, CA with Evan Friedmann, Kyle Boyar, TJ Martin, and Iain Oswald.

Catch the rest of the conversation on The Noid Knowledge podcast with Evan Friedman and be on the lookout for the full extended edit whenever we find the time to put it together!

How closely have you examined your deeply held beliefs? How confident are you that your beliefs are true? What are the reasons you have that give you your level of confidence in your belief?

In this throwback episode we take a critical look at beliefs. Beliefs of all kinds. Belief in God, karma, the law of attraction, ghosts, spirits – anything. In this episode of Isn’t Life Curious? I had the chance to sit down for a conversation with Anthony Magnabosco – a leader in a movement that seeks to critically examine and question deeply held beliefs through repeated non-confrontational questioning known as Street Epistemology. Anthony has spent the past eight years or so engaging strangers in short respectful conversations that challenge the participant to pick a deeply held belief and explain why they believe what they believe is true. In Socratic fashion, Street Epistemology relies on repeated questioning to peel away the “baggage” that is stacked on top of a belief so that the core ideas at the center of the belief can be exposed and examined.

Anthony has had several hundred chats (many of them on camera and uploaded to his YouTube channel) on a variety of claims including Gods, ghosts, karma, law of attraction, and a variety of social and political topics. He is a Founder and the current Executive Director of the new nonprofit organization Street Epistemology International. Anthony has given dozens of talks and workshops on Street Epistemology at conferences and events domestically and internationally in an attempt to spread practice of this method far and wide in hopes that it will help lead to a more reasonable and thoughtful society.
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Learn more about Street Epistemology at http://www.streetepistemology.com

In this throw back episode from the very beginning of the Isn’t Life Curious? series we join farmer and permaculturist Mark Shepard to discuss practical solutions to surviving and thriving on planet Earth. Mark is the CEO of Forest Agriculture Enterprises LLC, founder of Restoration Agriculture Development LLC and award-winning author of the book, Restoration Agriculture: Real-World Permaculture for Farmers. Mark has also been a farmer member of the Organic Valley cooperative, the worlds largest Organic Farmer’s marketing co-op, since 1995. He is most widely known as the founder of New Forest Farm, the 106-acre perennial agricultural savanna considered by many to be one of the most ambitious sustainable agriculture projects in the United States.

Throughout our conversation we talk about Mark’s journey to build New Forest Farm, lessons he has learned along the way, practical challenges to implementing permaculture and restorative agriculture techniques at scale, his experience studying permaculture under Bill Mollison, what modern permaculturists often misunderstand about permaculture, and much more!

You can learn more about New Forest Farm here: https://newforestfarm.us/
You can learn about Forest Agriculture Enterprises here: https://www.forestag.com/
You can learn about Restoration Agriculture Development here: http://www.restorationag.com/

Is life really all that special? Or is it just a happy accident that we are here?

Neil Manson, PhD is a philosopher and professor of philosophy specialized in tackling these very questions. An expert on philosophy of science and philosophy of religion, Dr. Manson and I dive down a metaphysical wormhole to explore the ways humans have tried to wrestle with our place in the universe. If there is a multiverse, what does that mean for our traditional concepts of God? If we live in a simulation, then what ethical obligations do I have to you or anyone else?

Take a deep breath and let’s have an existential crisis together on this episode of Isn’t Life Curious?!

Enjoy! Stay curious, and take it easy!

Do we even test for the right things?

Now that medical and adult-use cannabis programs have been around for some time, and with them mandated lab testing of products – we have a lot of data that we can begin to review in order to assess how well we are managing the quality of cannabis in the market.

In this episode we are joined by microbiologist and analytical technologist Kyle Boyar to confront the idea that there may be some things that regulators require testing for that will almost never show up in a sample, while there are certain toxins that show up more often than we might expect which are NEVER required for testing in any state in the country.

What’s going on? Let’s dive in and find out!

Continuing our series on the issues facing the Cannabis testing industry, we sit down with Josh Swider of Infinite Chemical Analysis Labs to discuss the ways that he and his lab have felt the effects of potency inflation and lab shopping over the past several years. One by one Josh has watched clients disappear after complaints that his THC potency numbers were not high enough compared to his competitors. This is a story all too familiar to most labs that have ever operated in the space. Eventually the requests to boost THC results became much more direct as clients started offering bribes including outright briefcases full of cash. When he denied these advances, he began receiving death threats.

In an effort to understand just how bad the problem was, Josh and his team began collecting products off the shelf and testing them in the lab to see how the results compared to the original test results on record for the product. The results were alarming. Not only did he find evidence of potency fraud, but he also ended up finding evidence of various contaminants in products that somehow originally tested “clean.”

In this episode Josh and I take time to discuss his journey, how the industry has gotten into the situation it is in, and some potential solutions for moving the industry in a positive direction.

Learn more about iCAL: https://infinitecal.com/

In this extended 2+ hour episode, Josh Smith of Therapeutic Health Choice, an analytical lab based out of Michigan, takes us on a deep dive into his experiences of Cannabis testing fraud as we explore some potential ways to fix issues like lab shopping and bring scientific integrity back to the cannabis industry.

About Josh:

Josh Smith is a seasoned biotech executive with a graduate degree in Clinical Microbiology and over 24 years of experience in biotechnology, molecular biology, and pharmaceutical R&D. He has played a key role in pioneering various projects, including founding Premium CBD Labs and later Vardera Inc., where he built a nationally recognized laboratory network from the ground up. His work has led to several molecular biology patents, and he has served as an expert witness in legal cases across Wisconsin, Illinois, and Michigan.

Josh is actively involved in shaping industry standards through his participation in international method committees like AOAC and ASTM. He has also lobbied in Wisconsin, advocating for improved policies in the lab testing industry. In late 2023, he was part of the team that successfully overturned the compliance testing requirement for Aspergillus spp. in the state of Oregon.

Beyond his corporate roles, Josh is passionate about advancing scientific knowledge and innovation. He serves on the Curriculum Advisory Board for the graduate-level Cannabis Applied Science Program at Fanshawe College (London, ON), is a member of the Cannabis Science and Research Organization (Oregon), and is an editor for the Cannabis and Psychedelic Science Journal.

This is the first of a series of conversations with lab owners and industry experts revolving around the topic of fraud, mismanagement, and poor regulations facing Cannabis testing labs. With issues ranging from THC potency inflation, under-reporting of contaminants, perverse incentive structures promoted by regulations, market manipulation, and more – this series dives deep into a very controversial issue to try to understand the problem at its foundation and find meaningful and practical solutions forward to restore trust and bring greater transparency to the Cannabis industry.

Yasha Kahn is one of the co-founders of MCR Labs and spends much of his time diving into data. Over the past several years, Yasha has been on a mission to collect publicly available Cannabis testing data and make it accessible to the industry in hopes of promoting fruitful research, discussion, and regulatory changes to positively impact the industry. In this episode we dive into some of the data that Yasha has gathered and start to unpack the story that it tells.

Link to the raw data: https://drive.google.com/drive/folders/1IIlgudS3b1rvxbupeMaR_BdeUQmz3pOZ?usp=drive_link

There is no doubt that when it comes to aroma, the Cannabis plant is LOUD. Depending on the variety, a host of smells can be found in Cannabis ranging from the sweet and floral to the funky, gassy, savory, and beyond. Chemist Twinkle Paryani has been trying to understand the chemistry behind the spectrum of aromas found in Cannabis and recently unearthed some interesting findings.

Abstrax Tech: https://abstraxtech.com/

Twinkle’s publication “Nonterpenoid Chemical Diversity of Cannabis Phenotypes Predicts Differentiated Aroma Characteristics“: https://pubs.acs.org/doi/full/10.1021/acsomega.4c03225

In this episode of Isn’t Life Curious? we join comedian and social media sensation Rodney Norman to talk about the meaning of life and what exactly he finds so funny about it all. Throughout the conversation we are joined by some of Rodney’s friends including Leonard, the World’s Worst Motivational Speaker, to unpack some of their most profound insights about what it means to be alive.

Get ready to discover all the answers you have ever sought about life and the universe! It’s all packaged up for you in this single hour long conversation – available to you for free! (plus shipping and handling)

You can learn more about Rodney and find tour dates, merch and more at www.rodneynorman.com

“Have a super freakin’ awesome day!”

Stay curious, and take it easy!