The Great Spin Up

Isomorphic Labs, Interface Design, Open Relating Agents


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Demis Hassabis's Isomorphic Labs raises $2.1B to solve all disease. Musk's case against OpenAI got thrown out on a timing technicality. Siri's becoming polyamorous and opening up to outside models.

Claude Opus 4.7 has started pushing back instead of agreeing. Meta's Tribe V2 models what's happening in your brain when you use a product. OpenHuman trends on GitHub. Land Library hits its first real product-market-fit moment — a thirty-year real estate veteran asking how to get more access.

TIMESTAMPS

(00:00) Cold open

(02:51) Weekly Check-in

(03:39) News

(28:26) Tools

(44:23) Building

(56:47) Rabbit Holes

(01:03:34) Open Questions

(01:17:23) Deep Dive — Interfaces

(01:47:52) AMA

RESOURCES

PEOPLE

Demis Hassabis — Google DeepMind co-founder, runs Isomorphic Labs

Johnny Ive — collaborating with OpenAI on a hardware project

Spike Jonze — directed "Her"

Stefan Sagmeister — designer, recent Long Now talk on progress

PROJECTS / COMPANIES / TOOLS

Cerebras Systems — AI chips, IPO'd with 160% pop on NASDAQ

Claude Opus 4.7 — Anthropic's model, now pushing back instead of agreeing

Gemini Flash Live 3.1 — Google voice model powering Hours

Hours — their voice-based micro-consulting agent

Isomorphic Labs — Hassabis's $2.1B drug-discovery raise

Land Library / Landbook — their land-relationship tool

OpenHuman — Mac-native open source agent, trending on GitHub

TBPN — podcast OpenAI acquired for ~$100M

Tribe V2 — Meta's brain-response modeling tool

FRAMEWORKS / CONCEPTS / LAWS

Bullshit Jobs — ~60% of white-collar work is unnecessary, per the book

Compute futures — arriving on the Chicago Mercantile Exchange

Gross National Happiness — Bhutan's alternative to GDP

Kaitiaki — Māori concept of land stewardship

Treaty of Waitangi — Māori–British translation gap on land ownership

PAPERS / ARTICLES / ESSAYS

Solve Everything — paper by Alex Wissner-Gross and Peter Diamandis

OTHER

Buns — Portuguese burger joint with a full http://localhost ops suite and AI banana cartoons

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The Great Spin UpBy Life-Time.co