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isoniazide
Trade NameINH
Indicationtuberculosis
ActionInhibits synthesis of mycobacterial cell wall
Therapeutic ClassAntitubercular
Pharmacologic Classnone
Nursing Considerations• can cause jaundice • may cause peripheral neuropathy, seizures, hepatitis • patient should avoid high amounts of tyramine (pickled meats, aged/smoked meats, alcohol, exotic/aged cheese) • monitor liver function tests • complete full course of therapy (6-12 months) • often used in combination with Rifampin
By Jon Haws, RN CCRN Alumnus4.4
158158 ratings
isoniazide
Trade NameINH
Indicationtuberculosis
ActionInhibits synthesis of mycobacterial cell wall
Therapeutic ClassAntitubercular
Pharmacologic Classnone
Nursing Considerations• can cause jaundice • may cause peripheral neuropathy, seizures, hepatitis • patient should avoid high amounts of tyramine (pickled meats, aged/smoked meats, alcohol, exotic/aged cheese) • monitor liver function tests • complete full course of therapy (6-12 months) • often used in combination with Rifampin

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