In this issue, we explore microsampling applications, benefits, and considerations for preclinical, clinical, bioanalytical research, and review two case studies on the topic.

Click here to download a PDF, readable version of Issue 16: https://www.altasciences.com/sites/default/files/2020-12/The%20Altascientist_issue16.pdf

CHAPTERS:

- 0:07 ― Section 1: Introduction

- 1:44 ― Section 2: Microsampling Benefits in Preclinical Research

- 3:30 ― Section 3: Microsampling Benefits in Clinical Research

- 6:56 ― Section 4: Bioanalytical Considerations

- 8:32 ― Section 5: Case Study ― Anti-Epileptic Drug Monitoring: Sample Preparation Using Impact-Assisted Extraction

- 10:18 ― Section 6: Case Study ― Determination of Rituximab Using a Surrogate Peptide

- 11:43 ― Section 7: Regulatory Aspect

- 15:21 ― Section 8: Scientific Guidance

- 15:47 ― Section 9: Pharmacokinetic and Statistical Analysis

About Altasciences:

Altasciences is an integrated drug development solution company offering pharmaceutical and biotechnology companies a proven, flexible approach to preclinical and clinical pharmacology studies, including formulation, manufacturing, and analytical services. For over 25 years, Altasciences has been partnering with sponsors to help support educated, faster, and more complete early drug development decisions. Altasciences’ integrated, full-service solutions include preclinical safety testing, clinical pharmacology and proof of concept, bioanalysis, program management, medical writing, biostatistics, clinical monitoring, and data management, all customizable to specific sponsor requirements. Altasciences helps sponsors get better drugs to the people who need them, faster.