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Issue 22 ― Nanomilling for Better Solubility and Improved Bioavailability
In this issue, discover how nanomilling can improve the solubulity and bioavailability of your drug.
Click here to download a PDF, readable version of Issue 22: https://www.altasciences.com/sites/default/files/2022-02/The-Altascientist_issue-22_Nanomilling.pdf
A crucial feature of drug development is bioavailability, defined as “the ability of a drug to be absorbed and used by the body.” For a drug to be bioavailable, it must first be soluble, meaning able to be dissolved, especially in water. Many drugs on the market today are poorly water soluble, and patent extensions or 505(b)(2) new patents become possible for formulation improvements delivered via nanomilling.
CHAPTERS:
- 0:00: Section 1 — Introduction
- 0:47: Section 2 — Solubility Classifications
- 2:33: Section 3 — Overcoming Solubility Challenges
- 3:51: Section 4 — The Benefits of Nanomilling
- 4:53: Section 5 — How Nanomilling Works
- 6:00: Section 6 — Maximizing Formulation
- 8:15: Section 7 — Case Study
- 11:14: Section 8 — Conclusion
About Altasciences:
Altasciences is an integrated drug development solution company offering pharmaceutical and biotechnology companies a proven, flexible approach to preclinical and clinical pharmacology studies, including formulation, manufacturing, and analytical services. For over 25 years, Altasciences has been partnering with sponsors to help support educated, faster, and more complete early drug development decisions. Altasciences’ integrated, full-service solutions include preclinical safety testing, clinical pharmacology and proof of concept, bioanalysis, program management, medical writing, biostatistics, clinical monitoring, and data management, all customizable to specific sponsor requirements. Altasciences helps sponsors get better drugs to the people who need them, faster.
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By The Altascientist
5
33 ratings
In this issue, discover how nanomilling can improve the solubulity and bioavailability of your drug.
Click here to download a PDF, readable version of Issue 22: https://www.altasciences.com/sites/default/files/2022-02/The-Altascientist_issue-22_Nanomilling.pdf
A crucial feature of drug development is bioavailability, defined as “the ability of a drug to be absorbed and used by the body.” For a drug to be bioavailable, it must first be soluble, meaning able to be dissolved, especially in water. Many drugs on the market today are poorly water soluble, and patent extensions or 505(b)(2) new patents become possible for formulation improvements delivered via nanomilling.
CHAPTERS:
- 0:00: Section 1 — Introduction
- 0:47: Section 2 — Solubility Classifications
- 2:33: Section 3 — Overcoming Solubility Challenges
- 3:51: Section 4 — The Benefits of Nanomilling
- 4:53: Section 5 — How Nanomilling Works
- 6:00: Section 6 — Maximizing Formulation
- 8:15: Section 7 — Case Study
- 11:14: Section 8 — Conclusion
About Altasciences:
Altasciences is an integrated drug development solution company offering pharmaceutical and biotechnology companies a proven, flexible approach to preclinical and clinical pharmacology studies, including formulation, manufacturing, and analytical services. For over 25 years, Altasciences has been partnering with sponsors to help support educated, faster, and more complete early drug development decisions. Altasciences’ integrated, full-service solutions include preclinical safety testing, clinical pharmacology and proof of concept, bioanalysis, program management, medical writing, biostatistics, clinical monitoring, and data management, all customizable to specific sponsor requirements. Altasciences helps sponsors get better drugs to the people who need them, faster.