Science Savvy

It HURTS! Pain and the Brain part 1


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Pain is weird. You only feel it in your brain… yet your brain has no pain receptors.

In part 1 of this 3-episode series, we unpack why pain is less a “signal” and more a decision your nervous system makes to feel it, shaped by reflexes, memory, mood, and context. You will learn why a hot stove makes you yank your foot back before you even feel anything, how “sharp” and “throbbing” travel on different nerve highways, and why chronic pain can become a disease of its own.

We discuss mind-bending paradoxes like phantom limb pain, referred pain (why heart attacks can hurt in your arm/jaw rather than your heart), and why two people with the same injury can rate pain totally differently.

 

Bibliography:

Greenwald BD (2012). Can the Brain Itself Feel Pain? BrainLine.

Derderian C, Shumway KR, Tadi P (2023). Physiology, Withdrawal Response. StatPearls.

Nicholas M et al. (2019). The IASP classification of chronic pain for ICD-11: chronic primary pain. PAIN 160(1): 19–27pmc.ncbi.nlm.nih.gov.

de Almeida KPO et al. (2020). Chronic Facial Pain: Trigeminal Neuralgia… Int J Environ Res Public Health 17(19):7012mdpi.com.

Mills SEE et al. (2019). Chronic pain: a review of its epidemiology… Br J Anaesth 123(2): e273–e283pmc.ncbi.nlm.nih.gov.

Limakatso K et al. (2020). The prevalence and risk factors for phantom limb pain… PLoS ONE 15(10):e0240431journals.plos.org.

Venda Nova C et al. (2020). Treatment outcomes in trigeminal neuralgia – a systematic review. World Neurosurg X 6:100070pubmed.ncbi.nlm.nih.gov.

Melzack R (1975). The McGill Pain Questionnaire: major properties and scoring methods. Pain 1(3):277–299sralab.org.

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Science SavvyBy fairleycarmen9