The 45th meeting between these two AFC South division rivals will pit Trevor Lawrence against rookie A.J. Richardson. Colts staring off another season in the AFC South and this year without their star player (for now), Jonathan Taylor.

Jaguars @ Colts I

During the NFL season and postseason here at The Prophet’s Picks, I will predict which NFL team will win before the games are played! Since 1995 I’ve done this successfully. During the off-season, I will keep you up to date with what’s going on with your favorite NFL team. Only the truth will be unleashed. No holds barred, no filter, no hogwash here on The Prophet’s Picks.

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Jaguars @ Colts I

Jaguars @ Colts I