In this episode of the JGO Podcast, we delve into a pivotal study examining the therapeutic role of lymphadenectomy in patients with early-stage epithelial ovarian cancer. Conducted by Yang and colleagues, the study compares oncologic outcomes, including disease-free survival and overall survival, between patients who underwent lymphadenectomy and those who did not. The episode explores key findings, such as the nuanced benefits observed in patients with serous histology, and discusses the broader implications for clinical practice. We also touch on the study’s limitations and the ongoing research that could further clarify lymphadenectomy's role in this patient population.

Lymphadenectomy in clinically early epithelial ovarian cancer and survival analysis (LILAC): a Gynecologic Oncology Research Investigators Collaboration (GORILLA-3002) retrospective study (https://doi.org/10.3802/jgo.2024.35.e750)