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In breaking neuroscience news, a study published in the Annals of Neurology has uncovered a potential game-changer in the treatment of ischemic stroke. Researchers have identified soluble ST2 (sST2) as a key mediator in brain edema formation, a major cause of death and disability post-stroke. By knocking out sST2 in a rat model, they found reduced brain swelling and improved blood-brain barrier integrity. This groundbreaking discovery not only links sST2 to post-stroke edema and mortality but also positions it as a promising therapeutic target for future stroke treatments. This could be a major step forward in stroke care, so stay tuned for more!