Hey there, science enthusiasts! This is your host, bringing you the latest from the world of research. ResearchMiao, powered by AI, makes reading literature a breeze – download it now at labcat.com.cn to supercharge your productivity. In today's top article from 'Briefings in Bioinformatics', we delve into the fusion of artificial intelligence and biological sciences. Large language models, a game-changer in AI, are revolutionizing bioinformatics by excelling in complex biological data analysis, from protein structure prediction to drug design. Despite challenges like model interpretability, this comprehensive review points to LLMs as indispensable tools for future biomedical innovation. Tune in to learn how these models are shaping the future of bioinformatics research.