The central message of this sermon is that God seeks true worshipers, regardless of their earthly status or background. The speaker argues that the biblical narrative consistently subverts human values and expectations, highlighting that what matters to God is not external factors like success, wealth, education, or social standing, but rather a person's inner state of being a true worshiper in spirit and truth. This means that anyone, regardless of their circumstances, can be considered by God for worship and relationship with Him. The speaker emphasizes that this inversion of human standards is a consistent theme throughout scripture, illustrated through stories such as Samuel anointing David, Daniel interpreting Nebuchadnezzar's dream, and Jesus' conversations in John 3 and John 4. Ultimately, the takeaway from this sermon is that God values inner character over external trappings, and that anyone can be chosen by Him for true worship and relationship.