Maybe you’ve heard of CAR-T cells, a type of cell you have in your body that is supercharged in a lab and put back in to fight things like cancer. Biomedical engineering expert Jeremy Green at Johns Hopkins and colleagues …

There’s a new technique that may revolutionize one type of T cell therapy, Elizabeth Tracey reports Read More »

CAR-T cells are a type of immune cell that have proven very effective for treating some types of cancer, yet limitations to their use exist. Biomedical engineering expert Jordan Green at Johns Hopkins says limitations including lengthy time and expense …

Can an injectable particle help supercharge your T cells? Elizabeth Tracey reports Read More »

Using polyester to wrap mRNA to create an injectable particle may soon enable targeting of your T cells to fight some cancers and autoimmune diseases.  That’s according to research by Jordan Green, a biomedical engineering expert at Johns Hopkins, and colleagues. …

Can an mRNA containing particle help direct your T cells to specific targets? Elizabeth Tracey reports Read More »

Let’s say I take one type of immune cell from your blood, grow it in a lab and use a virus to cause changes in that cell so it recognizes cancer. Then I put it back in your body to …

Temporary changes to T cells may empower new treatments for cancer and autoimmune disease, Elizabeth Tracey reports Read More »

Put together a shelf-stable particle with a polyester shell, a homing mechanism, and mRNA instructions, and what do you have? A new technology that may be able to train your own T cells inside your body to combat some types …

Messenger RNA can be used to stimulate T cells to fight cancer and autoimmune disease, Elizabeth Tracey reports Read More »

With several studies saying oxygen measurements are too low and one saying they’re too high, how much can pulse oximeters be trusted in those with darker skin? Rohan Mathur, a critical care medicine expert at Johns Hopkins, says that oft …

Trust but verify may be needed for pulse oximeters, Elizabeth Tracey reports Read More »

Critical care medicine relies on pulse oximeters, which estimate oxygen levels in someone’s blood, for many decisions regarding their care. Studies during the pandemic suggested the devices said there was more oxygen in the blood of someone with darker skin …

How do we account for opposite results from studies on pulse oximeters? Elizabeth Tracey reports Read More »

Do devices that measure oxygen levels in blood, known as pulse oximeters, measure too high or too low in those with darker skin? That’s the question now that results of an FDA funded study seem to contradict those of previous …

What does a recent FDA funded study on pulse oximeters show? Elizabeth Tracey reports Read More »

If you are a person with darker skin should you be worried about the levels of oxygen in your blood a pulse oximeter is giving? Critical care expert Rohan Mathur at Johns Hopkins says past studies looking at this issue …

Data from pulse oximeters can really impact patient care, Elizabeth Tracey reports Read More »

Do the devices known as pulse oximeters, which measure the amount of oxygen in someone’s blood, underestimate or overestimate this value in people with darker skin? Controversy swirls with release of data from an FDA funded study that runs counter …

What is up with pulse oximeters? Elizabeth Tracey reports Read More »