This week the boffins discuss the ANODE trial, published in The Lancet this year. This was a large multi centre placebo-controlled trial that found a reduction in infective morbidity when a single dose of IV Augmentin was given within 6 hours of instrumental birth.

Knight M, Chiocchia V, Partlett C, Rivero-Arias O, Hua X, Hinshaw K, Tuffnell D, Linsell L, Juszczak E, Enderby H, Thakar R. Prophylactic antibiotics in the prevention of infection after operative vaginal delivery (ANODE): a multicentre randomised controlled trial. The Lancet. 2019 May 13.