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【抗衰】长寿通路相关及槲皮素哪里来.m4a


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参考文献(找不到我的微信滴:A2016A05A)

1.  Campisi, J., Kapahi, P., Lithgow, G. J., Melov, S., Newman, J. C., & Verdin, E.  (2019).

From discoveries in ageing research to therapeutics for healthy ageing.

*Nature, 571*(7764), 183-192.

doi.org

2.  Justice, J. N., Nambiar, A. M., Tchkonia, T., et al.  (2019).

Senolytics in idiopathic pulmonary fibrosis: Results from a first-in-human, open-label, pilot study.

*EBioMedicine, 40*, 554-563.

doi.org

3.  López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M., & Kroemer, G.  (2013).

The hallmarks of aging.

*Cell, 153*(6), 1194-1217.

doi.org

4.  Sinclair, D. A., & LaPlante, M. D.  (2019).

*Lifespan: Why We Age—and Why We Don’t Have To.*

Atria Books.

5.  Zhu, Y., Tchkonia, T., Pirtskhalava, T., et al.  (2015).

The Achilles’ heel of senescent cells: From transcriptome to senolytic drugs.

*Aging Cell, 14*(4), 644-658.

doi.org

说明:

-  Campisi 2019 :系统总结了衰老生物学与治疗策略。

-  Justice 2019 :达沙替尼+槲皮素(D+Q)的首个人体临床试验。

-  López-Otín 2013 :经典衰老标志理论框架。

-  Sinclair 2019 :书籍,涵盖NAD+/Sirtuins与抗衰老机制。

-  Zhu 2015 :首次提出Senolytics概念及D+Q联用策略。

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