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 Summary:  Prescription drugs are so often approved for what they can do for you, and abused for where they can take you…and so it goes for Ketamine.  Valued for its ability to provide sedation and analgesia while maintaining cardiorespiratory stability, its abuse lies in its dissociative and hallucinogenic actions.  This episode is a brief discussion of the history of ketamine, what it is, how it might work in the brain, possible new indications as a prescription medication, and possible adverse effects of long-term ketamine abuse.  Recent studies indicate these troubling long-term effects may include memory impairment and diminished executive functioning i.e. ability to plan ahead and meet goals, display self-control and stay focused despite distraction.

Topics:

·      Dissociation 01:40

·      K – Hole 02:10

·      Dissociative Anesthetic Hallucinogen 03:00

·      Spravato (eskatamine) 03:55

·      Altered States 04:45

·      Hallucinations – Drugs to Prevent & Drugs to Induce 05:15

·      Balance 06:00

·      Chronic Pain Management, Neuropathy, Migraine, Refractory Depression 06:30

·      Response Time to Meds for Depression 07:00

·      Ketamine Mechanism of Action? 09:30

·      A Spiritual Experience? 11:20

·      Ketamine Side Effects 12:40

·      Close Monitoring 17:00

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