Examines Mitragyna speciosa (kratom), a tropical evergreen tree native to Southeast Asia and a relative of the coffee plant, long used for its medicinal and recreational properties. It explains that kratom’s effects vary with dosage—acting as a stimulant in small amounts and a sedative in larger doses—while noting its potential side effects and the presence of active alkaloids mitragynine and 7-hydroxymitragynine, which interact with opioid receptors. These compounds can provide pain relief and aid in opioid withdrawal without the same level of respiratory risk as traditional opiates. The discussion concludes by addressing the regulatory challenges and lack of quality control surrounding kratom’s sale and use in Western markets, where it remains largely unstandardized despite its growing popularity and ongoing medical research interest.
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