This week, I talk to my long time friend Kristin Luther an industry specialist in extracellular vesicles (EVs). We talk about her broad interest early in life, her foray into medical illustration, PhD years, and ultimate transition into industry. We also talk about the challenges facing EV biology (a topic near and dear to my own heart). Unexpectedly, we have a thoughtful conversation on the nature of vocation, facing challenges, and maintaining one's sense of curiosity-driven optimism.