Welcome to Cardiology Today – Recorded January 15, 2026. This episode summarizes 5 key cardiology studies on topics like Heart Failure Risk and Ethnicity Coding. Key takeaway: L. A. A. Stasis Links to A. F. Recurrence.

Article Links:

Article 1: Implications of Potential Undiagnosed HFpEF on Symptomatic Response With Coronary Revascularization. (JACC. Heart failure)

Article 2: Prediabetes, Subclinical Myocardial Injury or Stress, and Heart Failure Risk for Adults With Hypertension. (JAMA cardiology)

Article 3: Agreement of ethnicity reporting among patients with cancer with acute coronary syndrome: a national multiregistry analysis. (Heart (British Cardiac Society))

Article 4: Relationship Between Circulatory Stasis in the Left Atrial Appendage Detected by Cardiac Computed Tomography Angiography With Atrial Fibrillation Recurrence After Initial Catheter Ablation. (Journal of the American Heart Association)

Article 5: Plasma Biomarkers Associated With Heart Failure Hospitalization Among Patients With Atrial Fibrillation and Subtypes of Heart Failure. (Journal of the American Heart Association)

Full episode page: https://podcast.explainheart.com/podcast/l-a-a-stasis-links-to-a-f-recurrence-01-15-26/

Journal: JACC. Heart failure

PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41528276

Summary: F. pEF on Symptomatic Response With Coronary Revascularization. Patients diagnosed with Heart Failure with Preserved Ejection Fraction (H. F. pEF) experience poor quality of life and a substantial burden of coronary artery disease (C. A. D.). Clinical evidence providing guidance for revascularization in this patient population is currently limited. This limitation stems, in part, from the diagnostic complexity of Heart Failure with Preserved Ejection Fraction itself. Understanding the clinical implications of potential undiagnosed H. F. pEF on symptomatic response to coronary revascularization is critical for patient care.

Journal: JAMA cardiology

PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41533355

Summary: The precise relationship between coexisting prediabetes, subclinical myocardial injury, or stress and incident heart failure (H. F.) risk in adults with hypertension remains to be fully elucidated. This clinical area represents an important challenge for risk stratification and early intervention. Analyzing data from the Systolic Blood Pressure Intervention Trial (SPRINT) can provide valuable insights into these joint associations. Such research is crucial for enhancing preventive strategies and patient management.

Journal: Heart (British Cardiac Society)

PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41529954

Summary: Significant ethnic inequalities are observed in the management of patients with cancer who also experience acute coronary syndrome (A. C. S.). Given the under-representation of ethnic minority patients in conventional clinical trials, large national registries are frequently utilized for research in this population. A key challenge, however, is the variability and unclear quality of ethnicity coding within these large datasets. Improving the agreement of ethnicity reporting across national registries is fundamental for ensuring robust and equitable research outcomes.

Journal: Journal of the American Heart Association

PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41532555

Summary: Circulatory stasis within the Left Atrial Appendage (L. A. A.) is a significant area of investigation regarding atrial fibrillation (A. F.) recurrence following initial catheter ablation. Cardiac Computed Tomography Angiography (C. T. A.) offers a method for detecting this stasis. Understanding the relationship between Left Atrial Appendage stasis and post-ablation Atrial Fibrillation recurrence is crucial for improving patient selection and procedural outcomes. This knowledge could refine strategies to prevent tachyarrhythmia after intervention.

Journal: Journal of the American Heart Association

PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41532553

Summary: Atrial fibrillation and heart failure (H. F.) share a complex and bidirectional relationship, frequently leading to hospitalization. Multiplex screening of plasma proteins represents a powerful approach to identify biomarkers and underlying pathophysiological pathways associated with heart failure hospitalization in patients with atrial fibrillation. Furthermore, delineating distinct pathophysiological differences between Heart Failure with Reduced Ejection Fraction (H. F. rEF) and Heart Failure with Preserved Ejection Fraction (H. F. pEF) in this patient cohort is essential. Such insights can lead to more targeted therapies and improved risk stratification.

Today’s date is January 15, 2026. Welcome to Cardiology Today. Here are the latest research findings.

Article number one. Implications of Potential Undiagnosed H. F. pEF on Symptomatic Response With Coronary Revascularization. Patients diagnosed with Heart Failure with Preserved Ejection Fraction (H. F. pEF) experience poor quality of life and a substantial burden of coronary artery disease (C. A. D.). Clinical evidence providing guidance for revascularization in this patient population is currently limited. This limitation stems, in part, from the diagnostic complexity of Heart Failure with Preserved Ejection Fraction itself. Understanding the clinical implications of potential undiagnosed H. F. pEF on symptomatic response to coronary revascularization is critical for patient care.

Article number two. Prediabetes, Subclinical Myocardial Injury or Stress, and Heart Failure Risk for Adults With Hypertension. The precise relationship between coexisting prediabetes, subclinical myocardial injury, or stress and incident heart failure (H. F.) risk in adults with hypertension remains to be fully elucidated. This clinical area represents an important challenge for risk stratification and early intervention. Analyzing data from the Systolic Blood Pressure Intervention Trial (SPRINT) can provide valuable insights into these joint associations. Such research is crucial for enhancing preventive strategies and patient management.

Article number three. Agreement of ethnicity reporting among patients with cancer with acute coronary syndrome: a national multiregistry analysis. Significant ethnic inequalities are observed in the management of patients with cancer who also experience acute coronary syndrome (A. C. S.). Given the under-representation of ethnic minority patients in conventional clinical trials, large national registries are frequently utilized for research in this population. A key challenge, however, is the variability and unclear quality of ethnicity coding within these large datasets. Improving the agreement of ethnicity reporting across national registries is fundamental for ensuring robust and equitable research outcomes.

Article number four. Relationship Between Circulatory Stasis in the Left Atrial Appendage Detected by Cardiac Computed Tomography Angiography With Atrial Fibrillation Recurrence After Initial Catheter Ablation. Circulatory stasis within the Left Atrial Appendage (L. A. A.) is a significant area of investigation regarding atrial fibrillation (A. F.) recurrence following initial catheter ablation. Cardiac Computed Tomography Angiography (C. T. A.) offers a method for detecting this stasis. Understanding the relationship between Left Atrial Appendage stasis and post-ablation Atrial Fibrillation recurrence is crucial for improving patient selection and procedural outcomes. This knowledge could refine strategies to prevent tachyarrhythmia after intervention.

Article number five. Plasma Biomarkers Associated With Heart Failure Hospitalization Among Patients With Atrial Fibrillation and Subtypes of Heart Failure. Atrial fibrillation and heart failure (H. F.) share a complex and bidirectional relationship, frequently leading to hospitalization. Multiplex screening of plasma proteins represents a powerful approach to identify biomarkers and underlying pathophysiological pathways associated with heart failure hospitalization in patients with atrial fibrillation. Furthermore, delineating distinct pathophysiological differences between Heart Failure with Reduced Ejection Fraction (H. F. rEF) and Heart Failure with Preserved Ejection Fraction (H. F. pEF) in this patient cohort is essential. Such insights can lead to more targeted therapies and improved risk stratification.

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Heart Failure Risk, Ethnicity Coding, Catheter Ablation, Ethnic Inequalities, Atrial Fibrillation, Circulatory Stasis, Quality of Life, Hypertension, Cancer, Registry Analysis, Heart Failure Subtypes, Left Atrial Appendage, Heart Failure with Preserved Ejection Fraction, Prediabetes, Atrial Fibrillation Recurrence, Subclinical Myocardial Injury, Heart Failure Hospitalization, Coronary Artery Disease, Plasma Biomarkers, Revascularization, Acute Coronary Syndrome.

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