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LAB NOTES
By ApsEducation
LAB NOTES episodes
- Predicting Tensile Strength from Hardness: A Study of Eutectic SnBi Alloy
This presentation explores the relationship between nanoindentation (NI) hardness, Vickers microhardness, and ultimate tensile strength (σUTS) in a eutectic SnBi alloy. The researchers investigated the correlation coefficients between these properties and examined how microstructure, specifically interlamellar spacing, impacts hardness.
11 min - Unraveling the Potential of Berberine Analogs in Cancer Treatment: Targeting G-Quadruplex DNA
This audio explores the exciting world of cancer therapeutics research, focusing on a natural compound called berberine and its potential in fighting cancer.
Raman, Sankrith; Tailor, Isha; Kallahalla, Smriti; Cheung, Stephanie; Poon, Chloe; Parashar, Vivek, Brah, Harman. "Structure-activity relationship of berberine and G4 DNA reveals aromaticity’s effect on binding affinity." Journal of Emerging Investigators 202313 min - Unlocking Reaction Secrets: Using Benchtop NMR to Solve the Biginelli Condensation Mystery
Join us as we explore how scientists used cutting-edge benchtop 19F Nuclear Magnetic Resonance (NMR) spectroscopy to unravel the complexities of the Biginelli condensation, a key reaction for creating new drugs.
Chen, Rosie; Singh, Pratyush; Su, Sarah; Kocalar, Selin; Wang, Xina; Mandava, Neha; Venkatesan, Srishti; Ferguson, Adrienne; Rao, Aishi; Le, Emma; Rojas, Casey; Njoo, Edward. “Benchtop 19F Nuclear Magnetic Resonance (NMR) Spectroscopy Provides Mechanistic Insight into the Biginelli Condensation towards the Chemical Synthesis of Novel Trifluorinated Dihydro- and Tetrahydropyrimidinones as Antiproliferative Agents.” ACS Omega 2023. DOI: https://doi.org/10.1021/acsomega.3c0029015 min