Even in her first term, Arizona Senator Kyrsten Sinema has been unusually influential over the Democratic party's agenda — often by simply saying "no." But with her recent announcement that she is changing her party affiliation from Democrat to Independent, the balance of power within the Democratic party is shifting. What effects will her departure from the party have on the 118th Congress and President Biden’s agenda next year? We also check back in on what progress can be made before the end of the lame duck session on "last chance" bills for Democrats.

We're joined by Natalie Jennings, the Senior Politics editor at Vox, and Sophia Cai, Congressional reporter at Axios.