In this episode, our host, Melissa Knight, RN, MSN, CNE, addresses key questions concerning how to cultivate meaningful relationships with coworkers. Meaningful relationships, as a growing body of evidences supports, can have positive influence on attitudes and work behaviors. In this context, meaningful relationships is characterized as a relationship that is of personal significance and exudes caring support furthermore leading to encouragement and influence on others we are connected with and may lead to life-long connections. Although meaningful relationships within the workplace, requires time and energy, its benefit can offset staffing concerns, high turnover, incivility, bullying, and workplace violence. Leaders who engage with followers on a deeper level is highly relevant today in chaotic work environments in which almost 40% of workers are unsatisfied with their work relationships. Studies show that forming deeper connections with our coworkers helps to potentiate success and influence, as one becomes more engaged and motivated within a team setting. Each team member, subjected with meaningful relationships filled with trust and respect, may operate more effectively cultivated from a place of confidence and pursuing a common goal with others who exhibit compassion, empathy and appreciation. Valuing one’s uniqueness and truly listening and connecting with others, enables deeper loyalty. Standing on the principles of authenticity, honest and open communication, respect, trust, honesty and developing a culture of servant leadership may enable a deeper satisfaction within one’s career; furthermore exhibiting the essence of unconditional love. Establishing meaningful relationships helps develop confidence in one’s full potential which in turn leads to greater meaning in one’s job and ultimately affects the safety and quality of patient care.