This release contains only the music track from Base by Base Episode 187.

Song title: Leave a Gap for the Light
Original Base by Base episode: 187: Gapped scheduling: CRLX101 + olaparib Phase I trial

Article metadata:
Article title: Tumor-targeted top1 inhibitor delivery with optimized parp inhibition in advanced solid tumors: a phase i trial of gapped scheduling
Journal: Nature Communications
DOI: 10.1038/s41467-025-64509-5
Reference: Nature Communications (2025) 16:9457; https://doi.org/10.1038/s41467-025-64509-5

Lyrics:
Verse 1
Late-night monitors, steady fluorescent glow
A small white pill and a slow-release flow
Two ways to break what a tumor will hide
But we learned not to hit it all at once—
We learned to time the tide

Pre-Chorus
Hold back, then press in
Let the marrow breathe, let the next round begin
Damage shows up like a signal flare
In the roots of hair, in the blood we carry there

Chorus
Leave a gap for the light, leave a gap for the fight
Step, then strike—make the timing right
Thread the needle through a dangerous tune
Break the chain, trap the repair too soon
Leave a gap for the light, and we rise through the night

Verse 2
Nanoparticles drifting, patient and precise
A quiet kind of power at a measured price
No clash in the bloodstream, no crossing of lanes
Just a longer run and controlled release—
And a plan that reins in pain

Bridge
We don’t call it a cure, but we saw it move
A couple steps forward when there wasn’t much room
Some held their ground, some turned the page
And the warning signs stayed mostly manageable—
So we keep the courage, keep the gauge

Final Chorus
Leave a gap for the light, leave a gap for the fight
Step, then strike—make the timing right
Let the damage mark bloom, then close the door
Push the dose up near the edge, still asking for more
Leave a gap for the light, and we rise through the night