This week we're going to summarize all the tools we've discussed for alloimmunization and HDFN. We’re going to use case scenarios to walk through the individual diagnosis, management, surveillance, and treatment, followed by delivery and the neonatal course for each. Dr. Moise takes us through three different case scenarios - mild, moderate, and severe. See below for timestamps and some reference information!

2:57     Case 1 - 'Mild' Disease - First affected pregnancy with a low titer 

14:45   Case 2 – ‘Moderate’ Disease – Subsequent pregnancy with a moderate titer

32:47   Case 3 – ‘Severe’ Disease – Subsequent pregnancy with high titer or early need for IUTs

 

MCA MoM Score Calculators:

• Barcelona calculator: https://medicinafetalbarcelona.org/calc/
  • Select “Anemia” then “Cerebral Doppler”
• Perinatology: https://perinatology.com/calculators/MCA.htm

IUT Blood Volume Formulas

• IVT = volume of donor blood (78-80% hct) to raise the fetal hct 10 points = 0.02 x EFW (in grams)
• IPT = (GA (in weeks)) – 20 x 10